Protein Modification Reagents
eMolecules 2110448-99-0 | DBCO-NHCO-PEG4-acid | Broadpharm | MFCD31380393 | 552.624 | C30H36N2O8 | 98.000 | OC(=O)CCOCCOCCOCCOCCC(=O)NCCC(=O)N1Cc2ccccc2C#Cc2ccccc12 | 25mg | 353441826
DBCO-NHCO-PEG4-acid | Broadpharm | 2110448-99-0 | MFCD31380393 | 552.624 | C30H36N2O8 | 98.000 | OC(=O)CCOCCOCCOCCOCCC(=O)NCCC(=O)N1Cc2ccccc2C#Cc2ccccc12 | 25mg | 353441826
eMolecules 16024-60-5 | M-PEG3-CH2COOH | MFCD25959645 | 1g
Ambeed | (4-(Methoxymethoxy)-35-dimethylphenyl)boronic acid | 250mg | 717401502 | A326434 | 223128-32-3 | MFCD11856041 | 210.040 | C10H15BO4
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Medchemexpress LLC Dspe-peg2000-maleimide | 00-00-0 | 99.6% | C53H99N4O14P | 10MG
DSPE-PEG2000-Maleimide is a phospholipid-polyethylene glycol conjugate with a terminal maleimide group that enables covalent attachment to thiol-containing ligands. It incorporates into lipid bilayers to produce targeted liposomes and lipid nanoparticles, supporting targeted delivery research and ligand-directed surface modification.
- Terminal maleimide for specific thiol coupling.
- Amphiphilic lipid anchor for stable liposome insertion.
- PEG2000 spacer reduces opsonization and extends circulation time.
- High purity suitable for research applications (>99.5%).
- Soluble in DMF and DMSO with recommended handling procedures.
- Storage under nitrogen at -20°C; in solvent storage at -80°C extends stability.
Medchemexpress LLC m-PEG2-CH2CH2COOH | 209542-49-4 | MFCD20646047 | 97.0% | 192.21 g/mol | C8H16O5 | 500 MG
m-PEG2-CH2CH2COOH is a PEG2-based linker bearing a terminal carboxylic acid used as a spacer in the synthesis of PROTACs and for bioconjugation applications.
- Molecular formula C8H16O5 and molecular weight 192.21 g/mol.
- CAS number 209542-49-4.
- Typical purity 97.0% (NMR).
- Available in 250 mg, 500 mg, 1 g, 5 g, and larger sizes by quotation.
- Intended for use as a spacer/linker in medicinal chemistry and PROTAC synthesis.
- Store cold (examples indicate -20°C for long-term storage).
Medchemexpress LLC Mal-PEG2-oxyamine | 1146245-73-9 | 95.0% | C10H16N2O5 | 10MG
Mal-PEG2-oxyamine is a bifunctional PEG-based linker for use in the synthesis of PROTACs. It features a maleimide group and an aminooxy (oxyamine) group connected by a short PEG2 spacer, permitting orthogonal conjugation to thiol and carbonyl functionalities for targeted protein degradation research. The product is supplied with a reported purity of 95% and includes storage and solubility guidance for research applications.
- Bifunctional maleimide and aminooxy reactive groups.
- PEG2 spacer provides a short, flexible linkage.
- Enables selective conjugation to thiol and carbonyl partners.
- Reported purity supports synthetic and analytical use.
- Includes storage and solubility recommendations for stability.
Medchemexpress LLC Gly-gly-gly-PEG4-azide | 3070260-22-6 | 99.8% | 433.46 g/mol | C16H31N7O7 | 50 MG
Gly-gly-gly-PEG4-azide is a PEGylated tri-glycine linker bearing a terminal azide functional group used for bioconjugation and click chemistry. It facilitates attachment of payloads to peptides, proteins, or small molecules via copper-catalyzed azide-alkyne cycloaddition (CuAAC) or strain-promoted azide-alkyne cycloaddition (SPAAC).
- Enables CuAAC and SPAAC bioconjugation reactions
- High purity: 99.8% as supplied
- Molecular weight: 433.46 g/mol; formula C16H31N7O7
- Typical applications: ADC linker chemistry and payload attachment
- Recommended storage: -20 °C under inert gas; in solution: -80 °C (6 months)
- Available as a 50 MG vial